Pharmacokinetic Study of Oxidized Dextrans

A. A. Starostenko; A. V. Troitskii; V. S. Medvedev; E. P. Gulyaeva; T. N. Bystrova; V. A. Shkurupii

doi:10.1007/s11094-016-1373-6

Pharmacokinetic Study of Oxidized Dextrans

作者: Starostenko A.A.¹, Troitskii A.V.¹, Medvedev V.S.¹, Gulyaeva E.P.¹, Bystrova T.N.¹, Shkurupii V.A.¹
隶属关系:
1. Institute of Experimental and Clinical Medicine, Siberian Branch, Russian Academy of Medical Sciences
期: 卷 49, 编号 12 (2016)
页面: 795-797
栏目: Molecular-Biological Problems of Drug Design and Mechanism of Drug Action
URL: https://ogarev-online.ru/0091-150X/article/view/244294
DOI: https://doi.org/10.1007/s11094-016-1373-6
ID: 244294

如何引用文章

全文:

开放存取

##reader.subscriptionAccessGranted##
受限制的访问

订阅存取

详细
作者简介
参考
补充文件
统计

详细

Methods of obtaining biotinylated oxidized dextran (BTOD) and procedures for pharmacokinetic studies of BTOD and biotinylated dextran (BTD) are described. The pharmacokinetics results showed that there are no differences in principle between the oxidized and unoxidized dextrans. All studied dextrans were characterized by two-phase pharmacokinetic profiles after intraperitoneal and subcutaneous administration.

关键词

oxidized dextran, pharmacokinetics, biotin, immunoenzymatic assay

作者简介

A. Starostenko

Institute of Experimental and Clinical Medicine, Siberian Branch, Russian Academy of Medical Sciences