Отправить статью по E-mail Modern Technologies for Synthesizing Drug Substances: Toward Highly Efficient Drug Production
- Авторы: Narkevich I.A.1, Tarasov I.N.2, Golant Z.M.1, Alekhin A.V.3
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Учреждения:
- St. Petersburg State Chemico-Pharmaceutical Academy, Russian Ministry of Health
- MicroSpin MRT GmbH
- RF Ministry of Industry and Trade
- Выпуск: Том 49, № 11 (2016)
- Страницы: 760-764
- Раздел: Drug Synthesis Methods and Manufacturing Technology
- URL: https://ogarev-online.ru/0091-150X/article/view/244287
- DOI: https://doi.org/10.1007/s11094-016-1366-5
- ID: 244287
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Аннотация
Implementation of new technologies for synthesizing drug substances, e.g., continuous-flow microreactor synthesis of active drug substances (ADS) and asymmetric synthesis of intermediates and ADS using enzymes created by gene engineering methods, is highly significant for localizing ADS production in Russia. The possibility of using the existing Russian scientific infrastructure for rapid implementation of domestic production of a new ADS portfolio with the least operating losses, maximum economic efficiency, and high competitiveness was demonstrated.
Об авторах
I. Narkevich
St. Petersburg State Chemico-Pharmaceutical Academy, Russian Ministry of Health
Автор, ответственный за переписку.
Email: igor.narkevich@pharminnotech.com
Россия, 14 Prof. Popova St., St. Petersburg, 197022
I. Tarasov
MicroSpin MRT GmbH
Email: igor.narkevich@pharminnotech.com
Германия, 21 Zaarland St., Wolfach, 77709
Z. Golant
St. Petersburg State Chemico-Pharmaceutical Academy, Russian Ministry of Health
Email: igor.narkevich@pharminnotech.com
Россия, 14 Prof. Popova St., St. Petersburg, 197022
A. Alekhin
RF Ministry of Industry and Trade
Email: igor.narkevich@pharminnotech.com
Россия, 7 Kitaigorodskii Proezd, Moscow, 109074
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