Synthesis and Neurotropic Activity of New 7-Cyclohexyl-6,7,8,9-Tetrahydro-3H-Pyrazolo[3,4-c]-2,7-Naphthyridine-1,5-Diamines


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Аннотация

A method for synthesizing new tricyclic heterocyclic 7-cyclohexyl-6,7,8,9-tetrahydro-3H-pyrazolo- [3,4-c]-2,7-naphthyridine-1,5-diamines from 1,3-dichloro-7-cyclohexyl-5,6, 7,8-tetrahydro-2,7-naphthyridine-4-carbonitrile was elaborated. Investigation of the biological activity of the synthesized compounds showed that several of them exhibited pronounced neurotropic properties.

Авторлар туралы

S. Sirakanyan

A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia

Хат алмасуға жауапты Автор.
Email: shnnr@mail.ru
Армения, 26 Prosp. Azatutyan, 0014, Yerevan, 375014

E. Hakobyan

A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia

Email: shnnr@mail.ru
Армения, 26 Prosp. Azatutyan, 0014, Yerevan, 375014

A. Nikoghosyan

A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia

Email: shnnr@mail.ru
Армения, 26 Prosp. Azatutyan, 0014, Yerevan, 375014

R. Paronikyan

A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia

Email: shnnr@mail.ru
Армения, 26 Prosp. Azatutyan, 0014, Yerevan, 375014

I. Dzhagatspanyan

A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia

Email: shnnr@mail.ru
Армения, 26 Prosp. Azatutyan, 0014, Yerevan, 375014

I. Nazaryan

A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia

Email: shnnr@mail.ru
Армения, 26 Prosp. Azatutyan, 0014, Yerevan, 375014

A. Akopyan

A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia

Email: shnnr@mail.ru
Армения, 26 Prosp. Azatutyan, 0014, Yerevan, 375014

A. Hovakimyan

A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia

Email: shnnr@mail.ru
Армения, 26 Prosp. Azatutyan, 0014, Yerevan, 375014

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