Мақаланы E-mail арқылы жіберу Dehydration of 9a-Hydroxyandrost-4-ene-3,17-Dione in Organic Solvents
- Авторлар: Savinova T.S.1, Kazantsev A.V.2, Huy L.D.2, Lukashev N.V.1
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Мекемелер:
- M. V. Lomonosov Moscow State University, Faculty of Chemistry
- VietNam Academy of Science and Technology, Institute of Chemistry
- Шығарылым: Том 51, № 7 (2017)
- Беттер: 612-615
- Бөлім: Drug Synthesis Methods and Manufacturing Technology
- URL: https://ogarev-online.ru/0091-150X/article/view/244730
- DOI: https://doi.org/10.1007/s11094-017-1662-8
- ID: 244730
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Аннотация
An effective method of dehydrating 9_-hydroxyandrost-4-ene-3,17-dione by mineral acids in organic solvents, producing essentially quantitative formation of androsta-4,9(11)-diene-3,17-dione is proposed. Quantitative isomerization of the side product androsta-4,8(9)-diene-3,17-dione to target product was shown to be pssible.
Авторлар туралы
T. Savinova
M. V. Lomonosov Moscow State University, Faculty of Chemistry
Хат алмасуға жауапты Автор.
Email: savinova@org.chem.msu.ru
Ресей, Building 3, 1 Lenin Heights, Moscow, 119991
A. Kazantsev
VietNam Academy of Science and Technology, Institute of Chemistry
Email: savinova@org.chem.msu.ru
Вьетнам, 18 Hoàng Quoc Viet, Nghia Ðô, Cau Giay
Luu Huy
VietNam Academy of Science and Technology, Institute of Chemistry
Email: savinova@org.chem.msu.ru
Вьетнам, 18 Hoàng Quoc Viet, Nghia Ðô, Cau Giay
N. Lukashev
M. V. Lomonosov Moscow State University, Faculty of Chemistry
Email: savinova@org.chem.msu.ru
Ресей, Building 3, 1 Lenin Heights, Moscow, 119991
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