Studies on the Separation of Monoterpene Glycosides from Paeonia Veitchii Lynch. Herbs

Abstract

Traditional Chinese medicinal plant Paeonia veitchii Lynch. has a complicated chemical composition. For profound study of the medicinal value of Paeonia genus, systematic chromatographic investigations were carried out on n-butyl alcohol fractions of the ethanol extract for the separation of monoterpene glycoside compounds. Six compounds were isolated from the extract, which were identified on the basis of spectral analysis and physicochemical evidence. They are paeoniflorin (1), 4-O-methyloxypaeoniflorin (2), 4-O-methylpaeoniflorin (3), 4-O-ethylpaeoniflorin (4), paeonidanin (5), and 9-ethyl-neo-paeoniaflorin A (6). Compounds 2, 3, and 5 were isolated from this plant for the first time.