Current Trends in the Development of Technologies for Matrix Formulations with Modified Release (Review)

Abstract

Current aspects of the technology used to create matrix formulations ar presented. The main types of matrix are described depending on their behavior in the body; matrix-forming ingredients available on the Russian market are reviewed and the main principles determining their selection are discussed, along with the main technological principles underlying the preparation of matrix formulations. Technical factors affecting release of active substances from matrixes are addressed. Experimental data on release from matrix tablets based on composite polymer carriers are presented.