N’-(5H-Chromeno[2,3-b]pyridin-5-yl)-N-(cyclo)alkanoylhydrazines: Synthesis and Biological Activity

Мұқаба

Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Тек жазылушылар үшін

Аннотация

A series of N’-(5H-chromeno[2,3-b]pyridin-5-yl)-N-(cyclo)alkanoylhydrazines was prepared for the first time by the reaction of 5H-chromeno[2,3-b]pyridin-5-ol with (cyclo)alkanoylhydrazines in acetic acid medium and their antioxidant and antibacterial activities were investigated. Three alternative methods for the synthesis of N’-(5H-chromeno[2,3-b]pyridin-5-yl)-N-(cyclo)alkanoylhydrazines were proposed. The stability of the obtained compounds, depending on the structure of the hydrocarbon radical, their antioxidant and antibacterial activities were studied. The greatest antibacterial effect of N’-(5H-chromeno[2,3-b]pyridin-5-yl)-N-(cyclo)alkanoylhydrazines was shown against the mycomembrane bacteria Mycobacterium smegmatis me2 155.

Авторлар туралы

V. Gorokhov

Institute of Technical Chemistry of the Ural Branch of the Russian Academy of Sciences

Хат алмасуға жауапты Автор.
Email: Gorokhov_V.Yu@mail.ru
ORCID iD: 0000-0003-3829-5038
branch of the Perm Federal Research Center of the Ural Branch of the Russian Academy of Sciences Perm, Russia

T. Polyudova

Institute of Ecology and Genetics of Microorganisms of the Ural Branch of the Russian Academy of Sciences; Perm Agrarian-Technological University named after academician D.N. Pryanishnikov

Email: Gorokhov_V.Yu@mail.ru
ORCID iD: 0000-0003-2618-762X

branch of the Perm Federal Research Center of the Ural Branch of the Russian Academy of Sciences

Perm, Russia; Perm, Russia

S. Zabolotnykh

Institute of Technical Chemistry of the Ural Branch of the Russian Academy of Sciences

Email: Gorokhov_V.Yu@mail.ru
ORCID iD: 0000-0001-8307-0386

branch of the Perm Federal Research Center of the Ural Branch of the Russian Academy of Sciences

Perm, Russia

S. Gorokhova

Perm Agrarian-Technological University named after academician D.N. Pryanishnikov; Perm State National Research University

Email: Gorokhov_V.Yu@mail.ru
ORCID iD: 0000-0001-8609-0294
Perm, Russia; Perm, Russia

L. Chekanova

Institute of Technical Chemistry of the Ural Branch of the Russian Academy of Sciences

Email: Gorokhov_V.Yu@mail.ru
ORCID iD: 0000-0003-1792-6945

branch of the Perm Federal Research Center of the Ural Branch of the Russian Academy of Sciences

Perm, Russia

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