Particular features of lipid metabolism in psoriasis patients with concomitant metabolic syndrome
- 作者: Pashinyan A.G.1, Dontsova Y.V.2
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隶属关系:
- The Russian National Research Medical University named after N.I. Pirogov
- Voronezh State Medical Academy of a Name of N.N. Burdenko of Ministry of Health of Russia
- 期: 卷 90, 编号 4 (2014)
- 页面: 40-45
- 栏目: SHORT COMMUNICATION
- URL: https://ogarev-online.ru/0042-4609/article/view/116621
- DOI: https://doi.org/10.25208/0042-4609-2014-90-4-40-45
- ID: 116621
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Goal. To assess particular features of lipid metabolism in psoriasis patients with concomitant metabolic syndrome (MS). Materials and methods. Total cholesterol, triglycerides (TG) and high density lipoprotein cholesterol (HDL cholesterol) were determined in the blood serum of psoriasis patients by the enzymatic method using a spectrophotometer at the wavelength of 500 nm. The level of low-density lipoprotein cholesterol (LDL cholesterol) was determined by the calculation method using W. Friedewald’s formula (1972). The cholesterol atherogenicity ratio (CAR) was calculated by the formula: CAR = (Total cholesterol - HDL cholesterol) / HDL cholesterol Results. Patients suffering from psoriasis vulgaris are distinguished by lipid metabolism abnormalities characterized by the development of atherogenic dyslipidemia, increase in the total cholesterol, TG and LDL cholesterol in blood, reduction in the HDL cholesterol level and increased CAR. Patients with concomitant metabolic disorders have more obvious changes.
作者简介
A. Pashinyan
The Russian National Research Medical University named after N.I. Pirogov
编辑信件的主要联系方式.
Email: noemail@neicon.ru
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YE. Dontsova
Voronezh State Medical Academy of a Name of N.N. Burdenko of Ministry of Health of Russia
Email: ledn89@mail.ru
俄罗斯联邦
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