The first experience of non-interferon therapy of HCV infection in patients with Wilson-Konovalov’s disease


如何引用文章

全文:

详细

In the article we present three clinical observations demonstrating that HCV infection in patients with remission of Wilson disease causes an recrudescence of the disease, in one of the observations - decompensation of liver cirrhosis. In this study we first describe on the successful treatment of HCV infection with direct antiviral drugs in patients with Wilson disease. Establishment of all factors of liver damage and successful treatment (elimination of the virus, adequate lifelong medical treatment) allow to expect a favorable prognosis in patients with a combination of Wilson disease and HCV infection.

作者简介

T Rozina

Faculty of Medicine, M.V. Lomonosov Moscow State University; I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation

Email: alrozin@ya.ru
к.м.н., доцент фак-та фундаментальной медицины МГУ им. М.В. Ломоносова, https://orcid.org/0000-0001-5943-6181 Moscow, Russia

T Ignatova

Faculty of Medicine, M.V. Lomonosov Moscow State University; I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation

Email: tmignatova@gmail.com
д.м.н., проф. Moscow, Russia

S Fastovets

Faculty of Medicine, M.V. Lomonosov Moscow State University; I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation

Email: s.v.fastovets@gmail.com
аспирант фак-та фундаментальной медицины МГУ им. М.В. Ломоносова Moscow, Russia

E Starostina

Faculty of Medicine, M.V. Lomonosov Moscow State University

Email: starostinaee@gmail.com
к.м.н., Медицинский научно-образовательный центр МГУ им. М.В. Ломоносова Moscow, Russia

L Samokhodskaia

Faculty of Medicine, M.V. Lomonosov Moscow State University

Email: slm@fbm.msu.ru
к.м.н., доцент, Медицинский научно-образовательный центр МГУ им. М.В. Ломоносова Moscow, Russia

T Krasnova

Faculty of Medicine, M.V. Lomonosov Moscow State University; I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation

Email: krasnovamgu@yandex.ru
к.м.н., доцент фак-та фундаментальной медицины МГУ им. М.В. Ломоносова Moscow, Russia

参考

  1. Scheinberg H, Sternlieb I, eds. Wilson’s disease. Philadelphia: WB Saunders; 1984.
  2. Ferenci P. Regional distribution of mutations of the ATP7B gene in patients with Wilson disease: impact on genetic testing. Hum Genet. 2006;120:151-9. https://doi.org/10.1007/s00439-006-0202-5
  3. Ferenci P, Caca K, Loudianos G, Mieli-Vergani G, Tanner S, Sternlieb I, Schilsky M, Cox D, Berr F. Diagnosis and phenotypic classification of Wilson disease. Liver Int. 2003;23:139-42.
  4. Stremmel W, Meyerrose K.W, Niederau C, Hefter H, Kreuzpaintner G, Strohmeyer G. Wilson disease: clinical presentation, treatment, and survival. Ann Intern Med. 1991;115:720-6.
  5. EASL Clinical Practice Guidelines: Wilson’s disease. J Hepatol. 2012; 56:671-85. https://doi.org/10.1016/j.jhep.2011.11.007
  6. Rodriguez-Castro K.I, Hevia-Urrutia F.H., Sturniolo G.C. Wilson’s disease: A review of what we have learned. World J Hepatol. 2015;7(29):2859-70. https://doi.org/10.4254/wjh.v7.i29.2859
  7. Dienstag J.L. Hepatitis B virus infection. N Engl J Med. 2008; 359(14):1486-500.
  8. Miriam J Alter. Epidemiology of hepatitis C virus infection. World J Gastroenterol. 2007;13(17):2436-41.
  9. Chu N.S, Huang C.C. Wilson’s disease in Taiwan. Acta Neurol Taiwan. 2008;17(2):75-81.
  10. Deng H.H, Xu M. The clinical analysis of fulminant Wilson’s disease in patients with hepatitis B virus infection: a report of 13 cases. Zhonghua Nei Ke Za Zhi. 2016;55(8):628-30.
  11. Nalecz A, Socha J, Czlonkowska A, Gajda J. Wilson disease with HCV infections. Pediatr Pol. 1995;70(5):431-4.
  12. Lembowicz K, Kryczka W, Walewska-Zielecka B, Kubicka J. Wilson's disease coexisting with viral hepatitis type C: a case report with histological and ultrastructural studies of the liver. Ultrastruct Pathol. 1999;23(1):39-44.
  13. Розина Т.П., Рахимова О.Ю., Лопаткина Т.Н., Игнатова Т.М. Сочетание болезни Вильсона-Коновалова с хронической HCV-инфекцией (Клинико - морфологическое наблюдение). РЖГГК. 2004;14(2): 57-60.
  14. Manns M, Samuel D, Gane E.J, et al. Ledipasvir and sofosbuvir plus ribavirin in patients with genotype 1 or 4 hepatitis C virus infection and advanced liver disease: a multicentre, open - label, randomised, phase 2 trial. Lancet Infect Dis. 2016;16(6):685-97. https://doi.org/ 10.1016/S1473-3099(16)00052-9

补充文件

附件文件
动作
1. JATS XML
下载

版权所有 © Consilium Medicum, 2018

Creative Commons License
此作品已接受知识共享署名-非商业性使用-相同方式共享 4.0国际许可协议的许可。
 
 


Согласие на обработку персональных данных

 

Используя сайт https://journals.rcsi.science, я (далее – «Пользователь» или «Субъект персональных данных») даю согласие на обработку персональных данных на этом сайте (текст Согласия) и на обработку персональных данных с помощью сервиса «Яндекс.Метрика» (текст Согласия).