Physical Fatigue and Morphofunctional State of the Myocardium in Experimental Chronic Stress


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Resumo

The relationship between the development of skeletal muscle fatigue of a specific type in male Wistar rats and morphofunctional alterations in the myocardium in the posttraumatic stress disorder (PTSD) model has been investigated for the first time. The aggravation of oxidative stress in the cardiomyocytes and the related transformation of the cell structural components and the depletion of energy reserves in PTSD has been identified as one of the main factors that accelerate the onset of musculoskeletal fatigue.

Sobre autores

M. Kondashevskaya

Research Institute of Human Morphology

Autor responsável pela correspondência
Email: marivladiko@mail.ru
Rússia, Moscow, 117418

M. Chereshneva

Institute of Immunology and Physiology

Email: marivladiko@mail.ru
Rússia, Yekaterinburg, 620039

H. Downey

South Ural State University; University of North Texas Health Science Center

Email: marivladiko@mail.ru
Rússia, Chelyabinsk, 454080; Fort Worth, 76107

E. Manukhina

South Ural State University; Institute of General Pathology and Pathophysiology; University of North Texas Health Science Center

Email: marivladiko@mail.ru
Rússia, Chelyabinsk, 454080; Moscow, 125315; Fort Worth, 76107

O. Kuzhel

Vitebsk State Medical University

Email: marivladiko@mail.ru
Belarus, Vitebsk, 210009

S. Lazuko

Vitebsk State Medical University

Email: marivladiko@mail.ru
Belarus, Vitebsk, 210009

A. Sarapultsev

Institute of Immunology and Physiology; Yeltsin Federal University

Email: marivladiko@mail.ru
Rússia, Yekaterinburg, 620039; Yekaterinburg, Ural, 620002

M. Lapshin

South Ural State University

Email: marivladiko@mail.ru
Rússia, Chelyabinsk, 454080

M. Komelkova

South Ural State University

Email: marivladiko@mail.ru
Rússia, Chelyabinsk, 454080

V. Tseylikman

South Ural State University

Email: marivladiko@mail.ru
Rússia, Chelyabinsk, 454080

V. Chereshnev

Institute of Immunology and Physiology; Yeltsin Federal University

Email: marivladiko@mail.ru
Rússia, Yekaterinburg, 620039; Yekaterinburg, Ural, 620002

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