Age-Dependent Changes in Na+,K+-ATPase Activity and Lipid Peroxidation in Membranes of Erythrocytes during Cardiosclerosis Development in Rats
- 作者: Rebrova T.Y.1, Afanasiev S.A.1, Popov S.V.1
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隶属关系:
- Research Institute of Cardiology
- 期: 卷 161, 编号 2 (2016)
- 页面: 235-236
- 栏目: Article
- URL: https://ogarev-online.ru/0007-4888/article/view/237291
- DOI: https://doi.org/10.1007/s10517-016-3384-4
- ID: 237291
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详细
Activity of Na+,K+-ATPase was measured in erythrocyte ghosts of 4- and 12-month-old rats, intact and with postinfarction cardiosclerosis. Enhanced accumulation of secondary LPO products and reduced activity of Na+,K+-ATPase were observed in erythrocyte ghosts of 12-month-old rats. The development of postinfarction cardiosclerosis in 4-month-old rats was accompanied by enhanced accumulation of LPO products and decreased activity of Na+,K+-ATPase. In comparison with young rats with postinfarction cardiosclerosis, 12-month-old rats with this pathology were characterized by less pronounced decrease in Na+,K+-ATPase activity and increase in accumulation of LPO products in comparison with intact control.
作者简介
T. Rebrova
Research Institute of Cardiology
编辑信件的主要联系方式.
Email: rebrova@cardio-tomsk.ru
俄罗斯联邦, Tomsk
S. Afanasiev
Research Institute of Cardiology
Email: rebrova@cardio-tomsk.ru
俄罗斯联邦, Tomsk
S. Popov
Research Institute of Cardiology
Email: rebrova@cardio-tomsk.ru
俄罗斯联邦, Tomsk
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