Отправить статью по E-mail Peculiar Aspects in Influence of α1-Adrenoceptor Stimulation on Isolated Rat Heart
- Авторы: Zefirov T.L.1, Khabibrakhmanov I.I.1, Ziyatdinova N.I.1, Zefirov A.L.2
-
Учреждения:
- Department of Human Health Protection, Kazan (Volga Region) Federal University
- Department of Normal Physiology, Kazan Federal Medical University
- Выпуск: Том 162, № 1 (2016)
- Страницы: 4-6
- Раздел: Article
- URL: https://ogarev-online.ru/0007-4888/article/view/237858
- DOI: https://doi.org/10.1007/s10517-016-3530-z
- ID: 237858
Цитировать
Открытый доступ
Доступ предоставлен
Только для подписчиков
Аннотация
The study examined the effect of α1-adrenoceptor stimulation with methoxamine on chronotropic function of isolated heart perfused ex vivo according to Langendorff and cardiac chronotropy in vivo. Stimulation of α1-adrenoceptors in isolated heart induced gradually developing bradycardia, which progressed during several minutes. Similar stimulation in vivo produced a short-term bradycardia probably terminated by the compensatory influences in the whole organism. Comparison of the data obtained in both experimental paradigms during α1-adrenoceptor stimulation revealed unidirectional changes in cardiac chronotropy characterized with time-related peculiarities.
Об авторах
T. Zefirov
Department of Human Health Protection, Kazan (Volga Region) Federal University
Автор, ответственный за переписку.
Email: zefirovtl@mail.ru
Россия, Kazan, the Republic of Tatarstan
I. Khabibrakhmanov
Department of Human Health Protection, Kazan (Volga Region) Federal University
Email: zefirovtl@mail.ru
Россия, Kazan, the Republic of Tatarstan
N. Ziyatdinova
Department of Human Health Protection, Kazan (Volga Region) Federal University
Email: zefirovtl@mail.ru
Россия, Kazan, the Republic of Tatarstan
A. Zefirov
Department of Normal Physiology, Kazan Federal Medical University
Email: zefirovtl@mail.ru
Россия, Kazan, the Republic of Tatarstan
Дополнительные файлы
