Enviar artigo por via de e-mail Afobazole Alleviates Cognitive Rigidity in Experimental Model of Autism Spectrum Disorders
- Autores: Kapitsa I.G.1, Kalinina A.P.1, Alymov A.A.1, Voronina T.A.1, Seredenin S.B.1
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Afiliações:
- V. V. Zakusov Research Institute of Pharmacology
- Edição: Volume 168, Nº 2 (2019)
- Páginas: 238-241
- Seção: Article
- URL: https://ogarev-online.ru/0007-4888/article/view/242380
- DOI: https://doi.org/10.1007/s10517-019-04682-y
- ID: 242380
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Resumo
Afobazole (10 mg/kg) alleviated cognitive rigidity in BALB/c mice, a phenotypic model of autism spectrum disorders. It improved spatial memory and retraining in T-maze with drinking reinforcement and restored the retrieval of acquired skill during reversal learning in Morris water maze.
Sobre autores
I. Kapitsa
V. V. Zakusov Research Institute of Pharmacology
Autor responsável pela correspondência
Email: ingakap73@mail.ru
Rússia, Moscow
A. Kalinina
V. V. Zakusov Research Institute of Pharmacology
Email: ingakap73@mail.ru
Rússia, Moscow
A. Alymov
V. V. Zakusov Research Institute of Pharmacology
Email: ingakap73@mail.ru
Rússia, Moscow
T. Voronina
V. V. Zakusov Research Institute of Pharmacology
Email: ingakap73@mail.ru
Rússia, Moscow
S. Seredenin
V. V. Zakusov Research Institute of Pharmacology
Email: ingakap73@mail.ru
Rússia, Moscow
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