Profile of microRNA in Blood Plasma of Healthy Humans


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Resumo

Analysis of the plasma microRNA profile can be used for the diagnosis of various pathological and physiological conditions. Complete microRNA microprofiling is an extremely important task. Here we used microarray analysis allowing measurement of the expression of 2500 microRNA (MirBase, version 20). About 10% known microRNA were found in the plasma. Most of the detected microRNA (69 microRNA; ~30%) were encoded by mirtrons.

Sobre autores

M. Skurnikov

P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation; Bioclinicum Research and Engineering Center

Autor responsável pela correspondência
Email: mshkurnikov@gmail.com
Rússia, Moscow; Moscow

Yu. Makarova

P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation; V. A. Engelhard Institute of Molecular Biology, Russian Academy of Sciences

Email: mshkurnikov@gmail.com
Rússia, Moscow; Moscow

E. Knyazev

Bioclinicum Research and Engineering Center

Email: mshkurnikov@gmail.com
Rússia, Moscow

K. Fomicheva

P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation

Email: mshkurnikov@gmail.com
Rússia, Moscow

K. Nyushko

P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation

Email: mshkurnikov@gmail.com
Rússia, Moscow

E. Saribekyan

P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation

Email: mshkurnikov@gmail.com
Rússia, Moscow

B. Alekseev

P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation

Email: mshkurnikov@gmail.com
Rússia, Moscow

A. Kaprin

P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation

Email: mshkurnikov@gmail.com
Rússia, Moscow

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