Profile of microRNA in Blood Plasma of Healthy Humans
- Autores: Skurnikov M.Y.1,2, Makarova Y.A.1,3, Knyazev E.N.2, Fomicheva K.A.1, Nyushko K.M.1, Saribekyan E.K.1, Alekseev B.Y.1, Kaprin A.D.1
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Afiliações:
- P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation
- Bioclinicum Research and Engineering Center
- V. A. Engelhard Institute of Molecular Biology, Russian Academy of Sciences
- Edição: Volume 160, Nº 5 (2016)
- Páginas: 632-634
- Seção: Article
- URL: https://ogarev-online.ru/0007-4888/article/view/236848
- DOI: https://doi.org/10.1007/s10517-016-3235-3
- ID: 236848
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Resumo
Analysis of the plasma microRNA profile can be used for the diagnosis of various pathological and physiological conditions. Complete microRNA microprofiling is an extremely important task. Here we used microarray analysis allowing measurement of the expression of 2500 microRNA (MirBase, version 20). About 10% known microRNA were found in the plasma. Most of the detected microRNA (69 microRNA; ~30%) were encoded by mirtrons.
Sobre autores
M. Skurnikov
P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation; Bioclinicum Research and Engineering Center
Autor responsável pela correspondência
Email: mshkurnikov@gmail.com
Rússia, Moscow; Moscow
Yu. Makarova
P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation; V. A. Engelhard Institute of Molecular Biology, Russian Academy of Sciences
Email: mshkurnikov@gmail.com
Rússia, Moscow; Moscow
E. Knyazev
Bioclinicum Research and Engineering Center
Email: mshkurnikov@gmail.com
Rússia, Moscow
K. Fomicheva
P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation
Email: mshkurnikov@gmail.com
Rússia, Moscow
K. Nyushko
P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation
Email: mshkurnikov@gmail.com
Rússia, Moscow
E. Saribekyan
P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation
Email: mshkurnikov@gmail.com
Rússia, Moscow
B. Alekseev
P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation
Email: mshkurnikov@gmail.com
Rússia, Moscow
A. Kaprin
P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation
Email: mshkurnikov@gmail.com
Rússia, Moscow
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