Отправить статью по E-mail Descriptive statistics of disallowed regions and various protein secondary structures in the context of studying twisted β-hairpins
- Авторы: Torshin I.Y.1, Uroshlev L.A.2, Esipova N.G.2, Tumanyan V.G.2
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Учреждения:
- Department of Chemistry
- Engelhardt Institute of Molecular Biology
- Выпуск: Том 61, № 1 (2016)
- Страницы: 6-12
- Раздел: Molecular Biophysics
- URL: https://ogarev-online.ru/0006-3509/article/view/151887
- DOI: https://doi.org/10.1134/S0006350916010243
- ID: 151887
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Аннотация
A detailed analysis of polypeptide-chain backbone conformations was carried out for polypeptide-chain segments adjacent to β-turn regions, including the sites of disallowed conformations. A cross comparison of conformations was performed for disallowed regions of the Ramachandran plot and main types of β-turns and adjacent secondary structures. Based on the results, disallowed region 2 (II, II') in the Ramachandran plot was shown to coincide mainly with β-hairpins and, more exactly, twisted β-hairpins. The frequency of residues with angles ϕi, ψi that fall in region 2 (II, II') in the latter is 140 times higher than in common β-hairpins.
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Об авторах
I. Torshin
Department of Chemistry
Email: vladimir.tumanyan@gmail.com
Россия, Moscow, 119991
L. Uroshlev
Engelhardt Institute of Molecular Biology
Email: vladimir.tumanyan@gmail.com
Россия, Vavilova ul. 32, Moscow, 119991
N. Esipova
Engelhardt Institute of Molecular Biology
Email: vladimir.tumanyan@gmail.com
Россия, Vavilova ul. 32, Moscow, 119991
V. Tumanyan
Engelhardt Institute of Molecular Biology
Автор, ответственный за переписку.
Email: vladimir.tumanyan@gmail.com
Россия, Vavilova ul. 32, Moscow, 119991
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