The influence of electromagnetic radiation of extremely high frequencies on the pro- and antioxidant status of blood in experiments

Аннотация

The influence of electromagnetic radiation of extremely high frequencies in the noise mode on the level of the activity of proand antioxidant systems in a model of skin-flap ischemia was studied in vivo. Rats of the Wistar line were used in this work. The cutaneous reflex projection field of the animals was exposed once a day for 7 days in the post-operative period to electromagnetic radiation of an extremely high frequency in the range from 53.57 to 78.33 GHz with a dose of 1.2 mJ in the noise mode. The dynamics of proand antioxidant protection were compared to those of intact animals that were not irradiated. Using data on induced biochemiluminescence and estimation of malondialdehyde activity it was shown that irradiation in a course mode contributed to a decrease in the intensity of lipid peroxidation. In parallel we observed an increase in the total antioxidant reserves of blood and the activity of bioradical protection enzymes. Our findings suggest that electromagnetic radiation at extremely high frequencies in a noise mode has a regulatory impact on the state of proand antioxidant systems of the body; this can be used for the correction of postoperative ischemic disorders and the restoration of disturbed homeostasis.