Diode Laser Spectroscopy for Creating Effective Measuring Systems and Their Use in Biological and Medical Research


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Abstract

In this paper, we present the most important principles of diode laser spectroscopy, which allow one to create fundamentally new measuring systems for diverse applications in biology and medicine. Using the diode laser spectroscopy method and its primary hardware implementation the emission of gas molecules from skin of the hand was registered and ammonia skin emission was found to be dominant. The properties of exhaled air from patients in different states were determined with another special measuring complex of diode laser spectroscopy. It was shown that when the functional state of the body changes, the gas composition of molecular substances that are present in the exhaled air is altered indirectly and their levels vary significantly depending on the health of the individual. Our findings suggest that it is possible to study the specific functional properties of the human body to facilitate assessment of the health of an individual to determine whether pathological processes occur in the body at various stages of their severity using diode laser spectroscopy. This paper presents clinical and experimental data on this issue.

About the authors

Ya. Ya. Ponurovskii

Prokhorov General Physics Institute, Russian Academy of Sciences

Author for correspondence.
Email: Ponur1960@yandex.ru
Russian Federation, Moscow, 119991

V. Ya. Zaslavskii

Prokhorov General Physics Institute, Russian Academy of Sciences

Email: Ponur1960@yandex.ru
Russian Federation, Moscow, 119991

A. I. Nadezhdinskii

Prokhorov General Physics Institute, Russian Academy of Sciences

Email: Ponur1960@yandex.ru
Russian Federation, Moscow, 119991

M. V. Spiridonov

Prokhorov General Physics Institute, Russian Academy of Sciences

Email: Ponur1960@yandex.ru
Russian Federation, Moscow, 119991

D. B. Stavrovskii

Prokhorov General Physics Institute, Russian Academy of Sciences

Email: Ponur1960@yandex.ru
Russian Federation, Moscow, 119991

Yu. P. Shapovalov

Prokhorov General Physics Institute, Russian Academy of Sciences

Email: Ponur1960@yandex.ru
Russian Federation, Moscow, 119991

A. A. Karabinenko

Pirogov Russian National Research Medical University

Email: Ponur1960@yandex.ru
Russian Federation, Moscow, 117997

Yu. M. Petrenko

Pirogov Russian National Research Medical University

Email: Ponur1960@yandex.ru
Russian Federation, Moscow, 117997

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