A Study of the Oscillatory Components of the Skin Microhemodynamics in Mice by Laser Doppler Flowmetry


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Abstract

A skin blood flow was studied by laser doppler flowmetry. Fourteen male BALB/c mice were used. The skin blood flow was registered in the left hind paw. To measure the skin microhemodynamics, we proposed a protocol of animal immobilization with two types of anesthesia, injection with zoletil and inhalation with nitrous oxide. The borders of low-frequency intervals of oscillations of the microhemodynamics in mice have been determined; they coincided with those for humans and rats that were determined earlier.

About the authors

M. E. Astashev

Institute of Cell Biophysics

Author for correspondence.
Email: astashev@yandex.ru
Russian Federation, Pushchino, Moscow oblast, 142290

D. A. Serov

Institute of Fundamental Problems in Biology

Email: astashev@yandex.ru
Russian Federation, Pushchino, Moscow oblast, 142290

A. V. Tankanag

Institute of Cell Biophysics

Email: astashev@yandex.ru
Russian Federation, Pushchino, Moscow oblast, 142290

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