Atomic-force microscopy of erythrocytes and metabolic disorders in experimental diabetes mellitus and during the correction of diabetes with lipoic acid

V. V. Emelianov; D. V. Leontev; A. V. Ishchenko; T. S. Bulavintseva; E. A. Savateeva; I. G. Danilova

doi:10.1134/S0006350916050067

Atomic-force microscopy of erythrocytes and metabolic disorders in experimental diabetes mellitus and during the correction of diabetes with lipoic acid

Authors: Emelianov V.V.¹, Leontev D.V.¹, Ishchenko A.V.¹, Bulavintseva T.S.¹, Savateeva E.A.¹, Danilova I.G.¹
Affiliations:
1. Ural Federal University named after the first President of Russia B.N. Yeltsin
Issue: Vol 61, No 6 (2016)
Pages: 906-910
Section: Cell Biophysics
URL: https://ogarev-online.ru/0006-3509/article/view/152154
DOI: https://doi.org/10.1134/S0006350916050067
ID: 152154

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Abstract

Lipid peroxidation in blood plasma and red blood cells was shown to have minor effects on the state of the erythrocyte membranes in rats with alloxan diabetes. Administration of α-lipoic acid to rats with alloxan diabetes affected the metabolism of the animals and induced significant changes in erythrocyte morphology, as demonstrated by atomic-force microscopy.