Production of Xenogenic Bone Powder for Implants Using Supercritical Fluid Extraction


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A technology for production of an osteoplastic material (xenogenic bone powder) for implants was developed and brought into use. Implants made of this material can be used in dentistry, periodentistry, maxillofacial surgery, and other branches of medicine. A distinctive feature of the suggested technology is that it uses supercritical fluid extraction for deep defatting and purification of the material. The obtained material was tested for cytotoxicity using and in vitro model. The level of the material's cytotoxicity was reliably shown to be sufficiently low to make it applicable for medical implantation purposes.

作者简介

D. Smolentsev

OOO MedEngBio

Email: gmv7981@mail.ru
俄罗斯联邦, Penza

M. Gurin

OOO Cardioplant

编辑信件的主要联系方式.
Email: gmv7981@mail.ru
俄罗斯联邦, Penza

A. Venediktov

OOO Cardioplant

Email: gmv7981@mail.ru
俄罗斯联邦, Penza

S. Evdokimov

ZAO NPP MedEng

Email: gmv7981@mail.ru
俄罗斯联邦, Penza

R. Fadeev

Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences

Email: gmv7981@mail.ru
俄罗斯联邦, Pushchino, Moscow Region

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