Current State and Prospects of Production of Radionuclide Generators for Medical Diagnosis

Resumo

The article considers the production of radionuclides in nuclear reactors and proton accelerators for three main generators, ⁹⁹Mo/ ^99mTc, ⁸²Sr/ ⁸²Rb and ⁶⁸Ge/ ⁶⁸Ga, and shows the advantages of using radionuclide generators for production of radiopharmaceuticals. Germanium-68 is manufactured using cyclotrons with an energy of 23-30 MeV. Linear proton accelerators or cyclotrons with an energy of 70-160 MeV are used for production of Rubidium-82.